Iberet Folic-500 Special Precautions

Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemia where vitamin B₁₂ is deficient.
Where anemia exists, its nature should be established and underlying causes determined. Folic acid especially in doses >0.1 mg daily may obscure pernicious anemia, in that hematologic remission may occur while neurological manifestations remain progressive. Concomitant parenteral therapy with vitamin B₁₂ may be necessary in patients with vitamin B₁₂ deficiency. Pernicious anemia is rare in women of childbearing age and the likelihood of its occurrence along with pregnancy is reduced by the impairment of fertility associated with vitamin B₁₂ deficiency.
In older patients and those with conditions tending to lead to vitamin B₁₂ depletion, serum B₁₂ levels should be regularly assessed during treatment with Iberet-Folic 500.
Do not exceed the recommended dose.
There is the possibility of dark feces.
Do not give to patients who received repeated blood transfusion or non-iron deficiency anemia.
Long-term usage may cause iron accumulation.